Bryan Johnson Expresses Disappointment: No Observable Benefits from Injecting His Son’s Plasma

**Bryan Johnson’s Multigenerational Plasma Exchange: No Benefits Detected**

**Bryan Johnson’s Multigenerational Plasma Exchange Experiment**

Bryan Johnson, known for his reverse aging journey, recently conducted the world’s first multigenerational plasma exchange. The experiment involved Johnson, his 17-year-old son, and his 70-year-old father. The protocol was approved by a team of over 30 doctors with the goal of potentially influencing age-related brain decline. However, Johnson has now concluded that there were no benefits from the procedure. He shared his findings in a tweet, stating that he underwent six young plasma exchanges, one of which involved his son’s plasma.

**The Procedure and Results**

The multigenerational plasma exchange procedure involves removing a liter of blood from a young donor, which is then separated into its components, including red blood cells, white blood cells, platelets, and plasma. The plasma is then injected into the recipient’s veins in the hopes of rejuvenating the body and combating aging. Johnson and his son both participated by giving their blood. Johnson received his son’s plasma, while his own plasma was injected into his father. Despite the extensive testing of biomarkers, Johnson did not see any benefits from the procedure. He clarified that young plasma exchange may be beneficial for older populations or specific conditions, but it did not have a positive impact on him.

**The Young Blood Controversy**

The use of young plasma transfusions for anti-aging purposes has been a controversial topic. Ambrosia, a startup in California, previously offered young plasma transfusions for $8,000 per liter. However, the company shut down in 2019 after the FDA warned against these types of procedures. According to the FDA, there is no proven clinical benefit of using plasma from young donors to treat age-related diseases. They also expressed concerns about the safety of using these products without rigorous testing.

Plasma transfusions have been used for severe infections, burns, and blood disorders but have not been conclusively proven to have anti-aging effects. Some researchers have studied the effects of young blood transfusions on mice and observed signs of regeneration in their brains and muscles. However, these associations have not been confirmed in humans. Researchers have shifted their focus to identifying molecular factors responsible for age-related diseases rather than trying to reverse aging through plasma transfusions.

**Conclusion: Discontinuation of Therapy**

Bryan Johnson’s journey in the pursuit of anti-aging has led him to explore various methods, including young plasma transfusions. However, after conducting the multigenerational plasma exchange experiment, Johnson has concluded that there were no benefits in his case. He announced on Twitter that the therapy has been discontinued. The controversy surrounding young blood transfusions and the lack of scientific evidence supporting their effectiveness have led researchers to approach anti-aging research more cautiously, targeting specific diseases associated with aging instead.